Posts

Showing posts from February, 2018
Image
                   Is there any End to Huntington’s disease? Huntington’s disease is a fatal genetic disorder that causes the tolerant breakdown of nerve cells in the brain. It deteriorates a person’s physical and mental abilities during their prime working years and has no cure. Nowadays there are approximately 30,000 suggestive Americans and more than 200,000 at-risk of causing the disease. Symptoms the initial age is 30 to 50 and it gets chronic in the period between 10 to 25 year. Ultimately, the weakened individual causes to pneumonia, heart failure or other complications. Everyone has the gene that causes Huntington’s disease, but only Huntington’s disease and possibly pass it on to upcoming those that inherit the expansion of the gene will get the generation. Symptoms Include: Personality changes, mood swings & depression Forgetfulness & impaired judgment Unsteady gait & involuntary movements (chorea) Slurred speech, difficulty in swallowin
Image
Are Stem cells and Regenerative medicine living up to their promises? Stem cells are taken from a donor and put them into a patient to treat a disease or injury. Regenerative medicine makes use of cells, bio materials, and molecules to fix structures in the body that do not function properly due to disease or injury. However, however today the treatments of regenerative medicine are very low. However Cell therapies and regenerative medicine improve the health of patients with their potential representing a structural shift in healthcare by focusing on the causes of disease by repairing, replacing, or regenerating damaged cells in the body.                                                                                                 Early successes The earlier day’s cell therapy was done by the transfusion of blood, which is common in clinical trials nowadays. It is also used in case of severe burn and scald injuries by using their own cells when a pati
Image
                          Research and Transplants on adult stem cells Adult Stem cell is a broad type of stem cells, Latest research of adult stem cells has been fueled  by their abilities to divide and generate all the cell types of the organ from which they originate potentially regenerating the entire organ from a few cells. There are no such controversial issues with scientific researches for the use of adult stem cells, unlike the embryonic stem cells. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the destruction of an embryo. Adult stem cell transplants are already widely used to treat dozens of conditions in patients There are nearly 3,500 on-going or completed clinical trials (in patients) using adult stem cells, as listed in the National Institutes of Health/FDA-approved database. Already by 2007, there were at least 73 condi

Stem Cell Biomarkers and their mechanisms in Prostate Cancer

Image
Present there is little effective treatment available for castration resistant prostate cancer (PCa) , which is the cause for most of prostate cancer related deaths. Emerging evidence suggested that cancer stem cells might play an important role in resistance to traditional cancer therapies, and the studies of cancer stem cells (including specific isolation and targeting on those cells) might benefit the discovery of novel treatment of prostate cancer, especially castration resistant disease. Standard PCa treatment includes radical prostatectomy, radiotherapy, chemotherapy and castration (either by drug or by surgery, mainly for androgen sensitive PCa), as well as immunotherapy and palliative therapy (mainly for castration resistant PCa (CRPC)). CRPC is responsible for majority of the PCa-related deaths, and currently there are two major hypotheses of CRPC carcinogenesis, the adaptive mechanism and the selective mechanism. The adaptive mechanism suggests gene mutations in PC