Is there any End to Huntington’s
disease?
Huntington’s disease is a fatal genetic disorder that causes
the tolerant breakdown of nerve cells in the brain. It deteriorates a person’s
physical and mental abilities during their prime working years and has no cure.
Nowadays there are approximately 30,000 suggestive Americans and more than
200,000 at-risk of causing the disease.
Symptoms the initial age is 30 to 50 and it gets chronic in
the period between 10 to 25 year. Ultimately, the weakened individual causes to
pneumonia, heart failure or other complications. Everyone has the gene that
causes Huntington’s disease, but only Huntington’s disease and possibly pass it
on to upcoming those that inherit the expansion of the gene will get the generation.
Symptoms Include:
Personality
changes, mood swings & depression
Forgetfulness
& impaired judgment
Unsteady
gait & involuntary movements (chorea)
Slurred
speech, difficulty in swallowing & significant weight loss
Who Is At Risk
Every child of a parent with Huntington’s disease has a 50/50
chance of receiving the expanded gene that causes the disease. If the child has
not inherited this expanded gene, he or she will never develop the disease and
cannot pass it on to their children.
Research
For the
first time ,A system to model embryonic
stem cell have been developed by scientist by introducing early abnormalities in the way Huntington’s
neurons look, and how these cells form larger structures that had not
previously been associated with the disease.
Huntington’s
is straight frontward genetic culprit diseases. Total hundred percent of people
having mutated Huntington (HTT) form of the gene for developing the diseases.
Extra DNA is taken by mutation to produce longer protein then usual protein by
the gene
Researchers hope
that these new cells will be a further useful for studying the cellular and
molecular convolutions of Huntington’s disease and suggested a new model for humans which will be further useful for
the brain and other diseases
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