11^th Annual Conference on Stem Cell and Regenerative Medicine

Kidney not only produce urine but also plays major role in blood pressure control, that’s why it’s an important organ for living , if it get damaged or lost functionality it no longer regenerated. The main functional unit of Kidney is glomeruli and tubules , which are generated from Kidney progenitor cell during fetal life. The major reason why kidney cannot be able to regenerate is because the progenitor cell are lost before or soon after kidney development completes Researchers reported that with the help of human iPS cell nephrons can be prepared, although for regenerative medicine, precursor cells are required in large amount. Scientists tried for culturing kidney progenitor cells but the problem is that they are not preserved for more than three days. Between 1 to 20 days of culturing the progenitor cells recollect their function and grow up to 1800 times. Generally In vivo this cells disappears within 10 days. Although scientists using there technique through which

What is pancreatic stem cell ? Pancreatic progenitor cells are stem cells originating from the developing fore gut endoderm which have potential of differentiating into lineage specific progenitors, thus liable for the  pancreas development. Giving rise to exocrine as well as endocrine cells. Acinar cells are being established from exocrine cells. The Beta cell makes insulin, glucagon is secreted form alpha cells, somatostatin is secreted form delta cell while pancreatic polypeptide is secreted by PP-cells. Pancreatic stem cells have ability of regenerating beta cells It has been confirmed by the researchers that human pancreas contain progenitor cells stimulates by developing into glucose responsive beta cells. Thus, researchers are finding way towards rising regenerative cell therapies for type 1 diabetes patients. This will be a major challenge that stands in the way of inventing biological treatment for the disease. For the decades it has been postulated that

           Can Multiple Sclerosis be treated by Neural Stem Cells? Multiple sclerosis Multiple sclerosis is an autoimmune disease in which the body's immune system attacks its own tissues and disables the Brain and Spinal cord. And this immune system malfunction destroys myelin. It isn't clear why MS develops in some people and not others. A combination of genetics and environmental factors appears to be responsible. Symptoms Signs and symptoms of multiple sclerosis may vary from person to person and over the course of the disease depending on the location of affected nerve fibers. ·          Numbness or weakness in one or more limbs that typically occurs on one side of your body at     a time, or the legs and trunk ·          Prolonged double vision ·          Pain in parts of of your body ·         Electric-shock sensations that occur with certain neck movements, especially bending the        neck forward ·          Tremor, lac

Are Histone acts as a key for male Fertility?  Histone Histones have emerged as key players in the regulation of gene expression. However, that PTMs can directly impact chromatin it has been suggested that PTMs of core histones (H2A, H2B, H3, and H4) have the potential to govern chromatin function according to the so-called “histone code” hypothesis by recruiting specific binding proteins. combinations of histone marks at promoters and enhancers correlate with the developmental potential and fate of cells.10,11 In undifferentiated embryonic stem cells (ESCs), pluripotency maintenance genes (e.g., Nanog, Oct4, and Sox2) are marked with high levels of H3K4 methylation at their transcriptional start sites. Research Histones are basic proteins that confer order and structure to DNA and it plays an important role in gene regulation and earlier Researchers have identified that histone BigH1 acts as a key protein in stem cell differentiation to male sex cells.