11^th Annual Conference on Stem Cell and Regenerative Medicine

Cancer Stem Cell Cancer stem cell rise too many cells like tumor, therefore form a tumor Cancer stem cells are immolating cells. That can divide and. Such type cells have been found in human tumor. Might be targets for cancer treatments .There may be similarities between cancer stem cell and normal stem cell. Cancer stem cells have possibility to transform .cancer is identified in bone marrow .leukemia is major cancer disease in stem cell. Leukemia is most commonly diagnosed in children and adult. These are first identified in bone marrow. Cancer stem cell are initiating with leukemia. Cancer stem cells are rare in number and undifferentiated potential. There are many stages in cancer stem cells and the stem cells are heterogeneous. Stem cell survives much longer than normal cells .there is a chance to accumulate the genetic mutations. Stem cells are key to our normal development through adult hood. This determines how our organs muscles are formed and how they ...

Regenerative Medicine is used to Replace tissues and Organs which are been damaged by disease. It also helpful for the permanent damaged organs. This can be done through the cell based therapy or by using cell products. Most of the regenerative medicine is depend upon the endogenous developmental or repair process and stem cell plays a main role in regenerative medicine. And they are integral part of the Regenerative Medicine. The ability of stem cell is currently being researched by the doctors and scientists it can cure untreatable diseases like diabetes, heart failure stem cell also important in drug testing .These are used in Joints, Muscle pain, Ligaments. Regenerative Injection Treatment are using autologous platelet or plasma or bone marrow Tissue engineer is the branch of regenerative medicine. Cells are building block of tissues and Tissues are the main function in the body .Tissue engineering and Regenerative Medicine is the regeneration of cells and tissues and b...

Cartilage-Hair Hypoplasia One of the rarest genetic disease is Cartilage-Hair Hypoplasia characterisation characteristically, it lead to skeletal deformities and a weak immune system. It also affects in short stature (dwarfism) Primary alopecia condition is been generated by the disease having no pigment by the light fine hair. 15% of people are affected by this condition. Symptoms include: fine, sparse hair and eyebrows skeletal and spinal abnormalities short limb dwarfism anaemia low levels of white blood cells The inherited autosomal recessive is Cartilage-Hair Hypoplasia. Its means that this disease is been carried by both parents but generally no sign of it is been shown by their own. By uniparental disomy it can be inherited but in rare cases. That means instead of inheriting one copy from each parent the child inherits copies two chromosome from only one parent. In Amish or Finnish population, the Cartilage-Hair Hypoplasia is been seen the most. Both male ...

How Cancer Persists Stem cells are found in numerous tissues in the body, its life span is limited unlike with all other regular cells. They have the ability of dividing and renovate themselves for long time period. There unspecialized character justifies that ensuring cells convert into different cell type on time when one cell divides. Like, stem cells inside the bone marrow have ability of becoming bone. Fat and blood cells Likewise, there is believed that cancer stem cell is present in the main part of tumour, in the other hand there growth is also undefined and ability of self-renovate till they convert into new cancer cells. The major tumours treatment leaves cancer stem cell unmarked. Cancer stem cell can move undetectably even after treatment of major tumours effectively to the blood stream by the immune system to generate new tumours. This process is known as metastasis. These minor tumours become more aggressive year after and it’s really difficult to treat them. ...

Spinal cord consist of class of neuron named as sensory interneurons, this neurons plays the lead role in communicating information between parts of body and central nervous system, through which sense of touch is been enabled. Paralyzed people are seriously affected by the lack of touch. Scientists added a precise bone morphogenetic protein named as BMP4, and retinoic acid which is another signalling molecule, containing two type of mixture of sensory interneurons towards human embryonic stem cell i.e. sense that body is in space is a proprioception is given by DI 1 sensory interneurons on the other side DI3 sensory interneurons assist tem for feeling sense of pressure To convincing pluripotent stem cell the scientists found duplicate mixture of sensory interneurons which established while adding similar signalling molecules, this are formed by reprogramming the mature cells (skin cells) of patients. The method of reprogramming has ability of creating any cell type with main...

Kidney not only produce urine but also plays major role in blood pressure control, that’s why it’s an important organ for living , if it get damaged or lost functionality it no longer regenerated. The main functional unit of Kidney is glomeruli and tubules , which are generated from Kidney progenitor cell during fetal life. The major reason why kidney cannot be able to regenerate is because the progenitor cell are lost before or soon after kidney development completes Researchers reported that with the help of human iPS cell nephrons can be prepared, although for regenerative medicine, precursor cells are required in large amount. Scientists tried for culturing kidney progenitor cells but the problem is that they are not preserved for more than three days. Between 1 to 20 days of culturing the progenitor cells recollect their function and grow up to 1800 times. Generally In vivo this cells disappears within 10 days. Although scientists using there technique through which ...

What is pancreatic stem cell ? Pancreatic progenitor cells are stem cells originating from the developing fore gut endoderm which have potential of differentiating into lineage specific progenitors, thus liable for the  pancreas development. Giving rise to exocrine as well as endocrine cells. Acinar cells are being established from exocrine cells. The Beta cell makes insulin, glucagon is secreted form alpha cells, somatostatin is secreted form delta cell while pancreatic polypeptide is secreted by PP-cells. Pancreatic stem cells have ability of regenerating beta cells It has been confirmed by the researchers that human pancreas contain progenitor cells stimulates by developing into glucose responsive beta cells. Thus, researchers are finding way towards rising regenerative cell therapies for type 1 diabetes patients. This will be a major challenge that stands in the way of inventing biological treatment for the disease. For the decades it has been postulated ...